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Chemotherapy is the mainstay therapy for eye lymphoma. Therapies will be native (injected immediately into the attention) or systemic (given orally or injected right into a vein, underneath the pores and skin, or into the cerebrospinal fluid).
Native Remedy
Native chemotherapy consists of methotrexate or rituximab injected immediately into the vitreous humor. Methotrexate is a robust drug that kills most cancers cells. At decrease dosages, it’s used to deal with inflammatory autoimmune situations comparable to rheumatoid arthritis and psoriasis.
Rituximab is a monoclonal antibody that targets and attaches to a protein discovered on the floor of B cells. That is poisonous to B cells and leads to their demise.
Eye lymphoma has additionally been identified to reply to exterior beam radiation, in response to the American Academy of Ophthalmology. This can be a therapy that goals radiation at a particular a part of the physique (on this case, your eye or eyes) to kill most cancers cells.
Systemic Remedy
Systemic therapy impacts your complete physique. For systemic chemotherapy, it’s possible you’ll get methotrexate and rituximab, as you’ll with native therapy. The distinction is how they’re delivered — both orally or injected right into a muscle, a blood vessel, your spinal wire, or underneath your pores and skin. Different highly effective anticancer medicines used to deal with eye lymphoma embody:
- Etoposide (Toposar, Etopophos)
- Lenalidomide (Revlimid)
- Temozolomide (Temodar)
In case your medical doctors are recommending a second radiation methodology past native exterior beam radiation, it’ll in all probability be complete mind radiation, in response to the American Academy of Ophthalmology. Complete mind radiation is normally useful when eye lymphoma has unfold to the mind, which occurs in many individuals, in response to some analysis.
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